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HRID 338585作成日：2026年10月26日

1-(benzo[d][1,3]dioxol-5-yl)-N-(5-benzylpyridin-2-yl)cyclopropanecarboxamide → 1-(Benzo[d][1,3]dioxol-5-yl)-N-(5-isobutylpyridin-2-yl)cyclopropanecarboxamide

https://huagongshe.com/reaction/338585

反応式

関与物質

役割名称HCID仕込み量
反応物1-(benzo[d][1,3]dioxol-5-yl)-N-(5-benzylpyridin-2-yl)cyclopropanecarboxamideHCID 57895164—
反応物1-(benzo[d][1,3]dioxol-5-yl)-N-(5-bromopyridin-2-yl)cyclopropanecarboxamideHCID 59166163—
反応物HCID 178448254HCID 178448254—
生成物1-(Benzo[d][1,3]dioxol-5-yl)-N-(5-isobutylpyridin-2-yl)cyclopropanecarboxamideHCID 44236533—

反応手順

1-(Benzo[d][1,3]dioxol-5-yl)-N-(5-isobutylpyridin-2-yl)cyclopropanecarboxamide was synthesized using the procedure of 1-(benzo[d][1,3]dioxol-5-yl)-N-(5-benzylpyridin-2-yl)cyclopropanecarboxamide by reacting 1-(benzo[d][1,3]dioxol-5-yl)-N-(5-bromopyridin-2-yl)cyclopropanecarboxamide with isobutylzinc(II) bromide.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08889875B2
出典データセットuspto-grants-2014_11
ORD IDord-e31638f4906f4d8fbb8760972310108a
出典メモuspto-grants-2014_11