3-Isopropylaniline → 4-bromo-N-(3-isopropylphenyl)picolinamide

反応式

[Br:1][C:2]1[CH:7]=[CH:6][N:5]=[C:4]([C:8]([OH:10])=O)[CH:3]=1.[CH:11]([C:14]1[CH:15]=[C:16]([CH:18]=[CH:19][CH:20]=1)[NH2:17])([CH3:13])[CH3:12]>>[Br:1][C:2]1[CH:7]=[CH:6][N:5]=[C:4]([C:8]([NH:17][C:16]2[CH:18]=[CH:19][CH:20]=[C:14]([CH:11]([CH3:13])[CH3:12])[CH:15]=2)=[O:10])[CH:3]=1

参加物

反応物 2

HCID 4586793-Isopropylaniline

HCID 7351504-Bromopyridine-2-carboxylic acid

生成物 1

HCID 866958524-bromo-N-(3-isopropylphenyl)picolinamide

実験手順

In a manner similar to that describe in Preparation 34, 4-bromo-pyridine-2-carboxylic acid and 3-isopropylaniline were converted to the title compound.

出典と根拠

ORDレコード: ord-3700250d417745dda7e04a14ad50b4e0
出典データセット: uspto-grants-2014_11
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08889870B2

反応ノート

読み込み中…