関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 3-Bromo-4-hydroxybenzaldehyde | HCID 76308 | — |
| 反応物 | 2-Amino-4-(trifluoromethyl)benzenethiol | HCID 88042 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | HCID 136183493 | HCID 136183493 | — |
反応手順
In a N,N-dimethylformamide (DMF) solvent, a suspension of 3-bromo-4-hydroxybenzaldehyde (1.0 eq.) and 2-amino-4-(trifluoromethyl)benzenethiol (1.0 eq.) was heated at a temperature of 100° C. After cooling, DMF was removed therefrom under reduced pressure. Methylene chloride was added to the resultant solid, and the produced precipitate was filtered, and washed with methylene chloride to obtain a solid target product.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08889881B2 |
|---|
| 出典データセット | uspto-grants-2014_11 |
|---|
| ORD ID | ord-a60606d2f7fa4625a89673b064524efe |
|---|
| 出典メモ | uspto-grants-2014_11 |
|---|
