化工社化工社 化学情報印刷レポート · 研究参考用
Pivaloyl chloride → 2,2-Dimethyl-propionic acid 10-bromodecyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Pivaloyl chloride | HCID 62493 | — |
| 反応物 | 1-Decanol, 10-bromo- | HCID 104507 | — |
| 触媒 | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| 溶媒 | Pyridine | HCID 1049 | — |
| 生成物 | 2,2-Dimethyl-propionic acid 10-bromodecyl ester | HCID 57333781 | 85% |
反応手順
2,2-dimethyl-propionic acid 10-bromodecyl ester was prepared in 85% yield by treatment of 10-bromodecan-1-ol with trimethylacetyl chloride in the presence of pyridine and 4-dimethylaminopyridine at room temperature in dithlcromethane. After 18 hrs, the reaction was quenched by the addition of dilute hydrochloric acid worked up and filtered through silica to provide 2,2-dimethyl-propionic acid 10-bromodecyl ester.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08889894B2 |
| 出典データセット | uspto-grants-2014_11 |
| ORD ID | ord-628f7a29ee99450882d8c5c0698fc2e3 |
| 出典メモ | uspto-grants-2014_11 |