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Hydrochloric Acid → 2-(3,5-Diacetylphenyl)amino-4,6-diamino-1,3,5-triazine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | 1,3,5-Triazine-2,4-diamine, 6-chloro- | HCID 18831 | — |
| 反応物 | Cni H1894 | HCID 463010 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 2-(3,5-Diacetylphenyl)amino-4,6-diamino-1,3,5-triazine | HCID 484324 | 62.5% |
反応手順
Compound No. 13: A suspension of 3,5-diacetylaniline (1.95 g) in water (10 mL) was treated with 2-chloro-4,6-diamino-1,3,5-triazine (1.455 g) and concentrated HCl (0.1 mL) and heated at reflux for 20 min. After cooling the hydrochloride of Compound No. 13 separated as a white powder. This was filtered out, dissolved in 60 mL of boiling aqueous 75% methanol and treated with triethylamine (1.5 mL). On cooling, off-white flakes separated. Filtration and drying gave 1.79 g of 2-(3,5-diacetylphenyl)amino-4,6-diamino-1,3,5-triazine, mp 271°-2° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05733932 |
| 出典データセット | uspto-grants-1998_03 |
| ORD ID | ord-f5ab73fd88e543f2b4cd602c407b93f7 |
| 出典メモ | uspto-grants-1998_03 |