2,6-Dimethylbenzoic acid → 2,6-dimethyl-N-(2-methylcyclohexyl)benzamide

HRID 339415

反応式

HRID 339415 の反応式
[CH3:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]([CH3:11])[C:3]=1[C:4]([OH:6])=O.[CH3:12][CH:13]1[CH2:18][CH2:17][CH2:16][CH2:15][CH:14]1[NH2:19]>>[CH3:11][C:7]1[CH:8]=[CH:9][CH:10]=[C:2]([CH3:1])[C:3]=1[C:4]([NH:19][CH:14]1[CH2:15][CH2:16][CH2:17][CH2:18][CH:13]1[CH3:12])=[O:6]

参加物

3

反応物 2

HCID 124392,6-Dimethylbenzoic acidHCID 234322-Methylcyclohexylamine

生成物 1

HCID 251292162,6-dimethyl-N-(2-methylcyclohexyl)benzamide収率 59%

実験手順

Prepared in a similar manner to Example 162 using 2,6-dimethylbenzoic acid and 2-methylcyclohexylamine. Yield: 59%. 1H NMR (500 MHz, CDCl3): δ 0.88-0.94 (3H, dd), 1.14-1.89 (9H, m), 2.21-2.22 (6H, d), 3.39-3.45 (1H, m), 7.02-7.03 (2H, d), 7.12-7.15 (1H, t), 8.11-8.13 (1H, d). MS (M+H, 246.2).

出典と根拠

ORDレコード
ord-c843baabb77a4e979bef528bf706e8e8
出典データセット
uspto-grants-2014_11
特許番号
US08895050B2

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