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Hydrochloric Acid → 6-[(3,5-Diacetylphenyl)amino]purine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Potassium Hydroxide | HCID 14797 | — |
| 反応物 | Cni H1894 | HCID 463010 | — |
| 反応物 | 6-Chloropurine | HCID 5359277 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 6-[(3,5-Diacetylphenyl)amino]purine | HCID 12093260 | 90.4% |
反応手順
Compound No. 16: A suspension of 3,5-diacetylaniline (0.531 g) in water (10 mL) was treated with 6-chloropurine (0.464 g) and concentrated HCl (0.25 mL) and heated at reflux for 30 min. After cooling the mixture was treated with 6 mL of aqueous 1N KOH. The mixture was stirred for 10 min and the solid was filtered out, washed with water, and dried, to give 0.80 g of 6-[(3,5-diacetylphenyl)amino]purine, mp dec 340°-350° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05733932 |
| 出典データセット | uspto-grants-1998_03 |
| ORD ID | ord-0b3c68dde58a4f4fbcd3c8750233eef7 |
| 出典メモ | uspto-grants-1998_03 |