化工社化工社 化学情報印刷レポート · 研究参考用
Stannous chloride dihydrate → 4-(6-Methoxy-1,3-benzothiazol-2-yl)aniline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Stannous chloride dihydrate | HCID 61436 | — |
| 反応物 | 6-Methoxy-2-(4-nitrophenyl) benzothiazole | HCID 10660852 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 4-(6-Methoxy-1,3-benzothiazol-2-yl)aniline | HCID 391870 | 93.6% |
反応手順
Prepared as described in the Nitro Reduction section using 2-(4-nitrophenyl)-6-methoxybenzothiazole (5.0 g, 17.5 mmol) and tin (II) dichloride dihydrate (31.5 g, 0.14 mol) in EtOH (150 ml) to give the title compound (4.2 g, 93%) as a colourless solid after work-up and recrystallisation from EtOH.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08895313B2 |
| 出典データセット | uspto-grants-2014_11 |
| ORD ID | ord-15f369d2d1e442018b37cb1474605b38 |
| 出典メモ | uspto-grants-2014_11 |