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Butanedione → HCID 178432401、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Butanedione | HCID 650 | — |
| 反応物 | Toluene | HCID 1140 | — |
| 反応物 | 4,5-Pyrimidinediamine, 6-chloro- | HCID 78010 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | HCID 178432401 | HCID 178432401 | 72% |
反応手順
A mixture of 6-chloropyrimidine-4,5-diamine (1.4 g, 10 mmol) and 2,3-butanedione (2.0 g, 23 mmol) in toluene (35 mL) and methanol (10 mL) was stirred at reflux for 1 h. Upon cooling, the product precipitated and was collected by suction filtration and rinsed with a MeOH/Et2O mixture (ca. 1:2), then air dried to afford 6,7-dimethylpteridin-4-ol (1.4 g, 72%) as a gold powder.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08895568B2 |
| 出典データセット | uspto-grants-2014_11 |
| ORD ID | ord-cf819b3287c147ed84923bf362ed7613 |
| 出典メモ | uspto-grants-2014_11 |