関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Tetramethyl orthocarbonate | HCID 74613 | — |
| 反応物 | 1-(3-Bromophenyl)-2-hydroxy-2-methylpropane-1-sulfonamide | HCID 68291860 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 生成物 | 5-(3-Bromophenyl)-2-methoxy-6,6-dimethyl-5,6-dihydro-1,4,3-oxathiazine 4,4-dioxide | HCID 68359202 | — |
反応手順
A mixture of 500 mg of 1-(3-bromophenyl)-2-hydroxy-2-methylpropane-1-sulfonamide in 2 ml of tetramethoxymethane and 0.5 ml of acetic acid was stirred at 100° C. for 3 hours. After the removal of the solvent under reduced pressure, the residue (565 mg) was used in the next reaction without further purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08895547B2 |
|---|
| 出典データセット | uspto-grants-2014_11 |
|---|
| ORD ID | ord-da8c1461b04e494cb05814fd65140e10 |
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| 出典メモ | uspto-grants-2014_11 |
|---|
