関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| 反応物 | 3-Acetyl-5-bromopyridine | HCID 820423 | — |
| 生成物 | 1-(5-Bromopyridin-3-yl)-3-(dimethylamino)prop-2-ene-1-one | HCID 67057279 | — |
反応手順
An N,N-dimethylformamide dimethylacetal (2 ml) solution containing 1-(5-bromopyridin-3-yl)ethanone (100 mg) (WO2009/87224 A1) was stirred at 100° C. for 5 hours. The solvent was distilled away under reduced pressure, and a yellow solid of 1-(5-bromopyridin-3-yl)-3-(dimethylamino)prop-2-ene-1-one was thus obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08895585B2 |
|---|
| 出典データセット | uspto-grants-2014_11 |
|---|
| ORD ID | ord-9ea3052c2c8641589f76c41843130f54 |
|---|
| 出典メモ | uspto-grants-2014_11 |
|---|
