(5-Azidomethyl-furan-2-ylmethyl)-carbamic Acid Tert-Butyl Ester → HCID 60035026、化合物

HRID 34106ノート

反応式

HRID 34106 の反応式
[C:1]([O:5][C:6](=[O:18])[NH:7][CH2:8][C:9]1[O:10][C:11]([CH2:14][N:15]=[N+]=[N-])=[CH:12][CH:13]=1)([CH3:4])([CH3:3])[CH3:2]>C(O)C.[Pd].CC([O-])=O.CC([O-])=O.[Pb+2]>[C:1]([O:5][C:6](=[O:18])[NH:7][CH2:8][C:9]1[O:10][C:11]([CH2:14][NH2:15])=[CH:12][CH:13]=1)([CH3:4])([CH3:2])[CH3:3]

参加物

4

反応物 1

HCID 60053847(5-Azidomethyl-furan-2-ylmethyl)-carbamic Acid Tert-Butyl Ester

生成物 1

HCID 60035026HCID 60035026、化合物収率 101.9%

試薬・触媒・溶媒 2

HCID 131709914Lindlars catalyst触媒HCID 702Ethanol溶媒

実験手順

To a solution of 88.6 mg of (5-azidomethyl-furan-2-ylmethyl)-carbamic acid tert-butyl ester in 3 mL of ethanol was added 30 mg of Lindlar catalyst, stirred at room temperature under hydrogen atmosphere for 15 hours, the catalyst filtered off, and the solvent was evaporated, to afford 81 mg of the title compound as a colorless oil.

後処理

  1. filtrationthe catalyst filtered off
  2. customthe solvent was evaporated

出典と根拠

ORDレコード
ord-c1cd73bbdc5141dab72dbd3f5b96d8e6
出典データセット
uspto-grants-2008_09
特許番号
US07429609B2

反応ノート

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