化工社化工社 化学情報印刷レポート · 研究参考用
Sodium Hydroxide → 4-Chloro-6-methyl-7-(2,5-dihydropyrrol-1-yl-carbonyl)-quinazoline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 反応物 | 3-Pyrroline | HCID 66059 | — |
| 反応物 | 6-Methyl-4-oxo-3,4-dihydro-quinazoline-7-carboxylic acid | HCID 136363910 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | 4-Chloro-6-methyl-7-(2,5-dihydropyrrol-1-yl-carbonyl)-quinazoline | HCID 86632696 | — |
反応手順
Prepared analogously to Example 2b or 2c from 6-methyl-4-oxo-3,4-dihydro-quinazoline-7-carboxylic acid, thionyl chloride, 2,5-dihydropyrrole, sodium hydroxide solution and dichloromethane.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07429597B2 |
| 出典データセット | uspto-grants-2008_09 |
| ORD ID | ord-43e80a9573df46fb99ae35d42496dc0e |
| 出典メモ | uspto-grants-2008_09 |