反応式
[ClH:1].C1(C)C=CC=CC=1.[CH3:9][CH:10]([N:19]1[CH2:23][CH2:22][CH2:21][CH2:20]1)[CH:11]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)[OH:12]>C(O)(C)C>[ClH:1].[CH3:9][CH:10]([N:19]1[CH2:23][CH2:22][CH2:21][CH2:20]1)[CH:11]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)[OH:12]参加物
5
実験手順
adding a solution of hydrogen chloride in isopropanol to a toluene solution of [R-(R*,S*)]-β-methyl-α-phenyl-1-pyrrolidineethanol or its enantiomer at about 10° to about 15° C. and maintaining a reaction temperature of about 10° to about 25° C. to form [R-(R*,S*)]-β-methyl-α-phenyl-1-pyrrolidineethanol hydrochloride or its enantiomer;
後処理
- temperaturemaintaining a reaction temperature of about 10° to about 25° C.
出典と根拠
- ORDレコード
- ord-291ec677f243435d9c65ff0f059cfb75
- 出典データセット
- uspto-grants-1999_01
- 特許番号
- US05856492
関連ノート
読み込み中…