Peracetic Acid → Quinoline 1-oxide

HRID 34262

反応式

HRID 34262 の反応式
C(OO)(=[O:3])C.[N:6]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[CH:9]=[CH:8][CH:7]=1>>[N+:6]1([O-:3])[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[CH:9]=[CH:8][CH:7]=1

参加物

3

反応物 2

HCID 6585Peracetic AcidHCID 7047Quinoline

生成物 1

HCID 15366Quinoline 1-oxide

実験手順

Peracetic acid (7.5 mL, 39 mmole, 40%) and quinoline (5 g, 39 mmole) were stirred for 2 hours. Much of the acetic acid was removed from the reaction mixture in vacuo. The resulting residue was dissolved in methylene chloride (50 mL) and washed twice with saturated sodium bicarbonate solution. After drying over MgSO4 the solvent was evaporated and the residue was triturated with ether. The resulting tan solid was collected by filtration. This material was carried on without further characterization.

後処理

  1. customMuch of the acetic acid was removed from the reaction mixture in vacuo
  2. dissolutionThe resulting residue was dissolved in methylene chloride (50 mL)
  3. washwashed twice with saturated sodium bicarbonate solution
  4. dry with materialAfter drying over MgSO4 the solvent
  5. customwas evaporated
  6. customthe residue was triturated with ether
  7. filtrationThe resulting tan solid was collected by filtration

出典と根拠

ORDレコード
ord-fbb987f1da9849cb93d557b6a2157e9e
出典データセット
uspto-grants-1988_08
特許番号
US04761403

関連ノート

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