Potassium Carbonate → HCID 54349857、化合物

HRID 342746ノート

反応式

HRID 342746 の反応式
[CH3:1][C:2]([NH:11][C:12](=[O:21])[C:13]1[CH:18]=[C:17]([Cl:19])[CH:16]=[C:15]([Cl:20])[CH:14]=1)([CH3:10])[C:3]([CH2:5][O:6]C(=O)C)=[O:4].C(=O)([O-])[O-].[K+].[K+]>CO>[CH3:10][C:2]([NH:11][C:12](=[O:21])[C:13]1[CH:18]=[C:17]([Cl:19])[CH:16]=[C:15]([Cl:20])[CH:14]=1)([CH3:1])[C:3]([CH2:5][OH:6])=[O:4]

参加物

4

反応物 2

HCID 11430Potassium CarbonateHCID 53897658HCID 53897658、化合物

生成物 1

HCID 54349857HCID 54349857、化合物収率 98%

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

N-(1',1'-dimethyl-3'-acetoxyacetonyl)-3,5-dichlorobenzamide (5.0 gm, 0.15 m) was treated with potassium carbonate (0.21 gm, 0.0015 m) in 250 ml methanol at room temperature for 12 hours. The methanol was removed by a vacuum, the residue was taken up in ether and washed successively with saturated sodium bicarbonate, water and brine. Drying of the ether solution followed by removing the solvent yielded 4.0 gm (98%) of pure product.

後処理

  1. customThe methanol was removed by a vacuum
  2. washwashed successively with saturated sodium bicarbonate, water and brine
  3. dry with materialDrying of the ether solution
  4. customby removing the solvent

出典と根拠

ORDレコード
ord-16925c9af55b49cfbdfc4c1594cf30d8
出典データセット
uspto-grants-1999_01
特許番号
US05859063

反応ノート

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