Water → HCID 54377907、化合物

HRID 342978

反応式

HRID 342978 の反応式
[Cl:1][C:2]1[C:10]([Cl:11])=[C:9]([O:12][C:13]([F:16])([F:15])[F:14])[CH:8]=[CH:7][C:3]=1[C:4](F)=[O:5].[OH2:17]>>[Cl:1][C:2]1[C:10]([Cl:11])=[C:9]([O:12][C:13]([F:16])([F:15])[F:14])[CH:8]=[CH:7][C:3]=1[C:4]([OH:17])=[O:5]

参加物

3

反応物 2

HCID 962WaterHCID 539612062,3-Dichloro-4-trifluoromethoxybenzoyl fluoride

生成物 1

HCID 54377907HCID 54377907、化合物

実験手順

A suspension of crude 2,3-dichloro-4-trifluoromethoxybenzoyl fluoride (2 g, containing mixed antimony halides) in water was stirred vigorously for 24 hours. The mixture was extracted with dichloromethane and filtered. The organic layer was washed with hydrochloric acid (2M), aqueous sodium chloride solution and extracted into sodium carbonate solution (2M). The aqueous extract was acidified to pH1 and the solid was filtered off and washed with water to give 2,3-dichloro-4-trifluoromethoxybenzoic acid (0.6 g) as a white solid mp 123°-126° C.

後処理

  1. extractionThe mixture was extracted with dichloromethane
  2. filtrationfiltered
  3. washThe organic layer was washed with hydrochloric acid (2M), aqueous sodium chloride solution
  4. extractionextracted into sodium carbonate solution (2M)
  5. extractionThe aqueous extract
  6. filtrationthe solid was filtered off
  7. washwashed with water

出典と根拠

ORDレコード
ord-5eeace1dbc7b47999c4c3f943350402d
出典データセット
uspto-grants-1999_01
特許番号
US05859283

関連ノート

読み込み中…