Ethanol → 2-(6-Methyl-1H-indol-3-yl)ethan-1-amine

HRID 343451ノート

反応式

HRID 343451 の反応式
[CH3:1][C:2]1[C:10](Br)=[C:9]2[C:5]([C:6]([CH2:12][CH2:13][NH2:14])=[CH:7][NH:8]2)=[CH:4][CH:3]=1.C(O)C>C(N(CC)CC)C>[CH3:1][C:2]1[CH:10]=[C:9]2[C:5]([C:6]([CH2:12][CH2:13][NH2:14])=[CH:7][NH:8]2)=[CH:4][CH:3]=1

参加物

4

反応物 2

HCID 702EthanolHCID 15274383HCID 15274383、化合物

生成物 1

HCID 1900062-(6-Methyl-1H-indol-3-yl)ethan-1-amine

試薬・触媒・溶媒 1

HCID 8471Triethylamine溶媒

実験手順

A sample of 6-methyl-7-bromo-1 H-indole-3-ethanamine was contacted with Pd/C H2 in the presence of ethanol and triethylamine. The resulting material was evaporated and partitioned between base/CHCl3. The organic phase was dried, concentrated, and dried. The resulting material was taken up into methanol and added to ethereal HCl. The resulting material was washed and vacuum dried.

後処理

  1. customThe resulting material was evaporated
  2. custompartitioned between base/CHCl3
  3. customThe organic phase was dried
  4. concentrationconcentrated
  5. customdried
  6. additionadded to ethereal HCl
  7. washThe resulting material was washed
  8. customvacuum dried

出典と根拠

ORDレコード
ord-63cb0fb11e5e404dbf2452123b65fdb4
出典データセット
uspto-grants-1999_01
特許番号
US05861425

反応ノート

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