化工社化工社 化学情報印刷レポート · 研究参考用
Triethylamine → 3-(2-Ethyl-6-methylphenyl)-1-methyl-2-thioxo-imidazolidin-4-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | 2-Ethyl-6-methylphenyl isothiocyanate | HCID 144188 | — |
| 反応物 | Ethyl N-methylaminoacetate hydrochloride | HCID 171173 | — |
| 溶媒 | Chloroform | HCID 6212 | — |
| 生成物 | 3-(2-Ethyl-6-methylphenyl)-1-methyl-2-thioxo-imidazolidin-4-one | HCID 85701470 | 60% |
反応手順
The title compound was prepared by the procedure described in Example 1 using 8.9 g of 2-ethyl-6-methylphenyl-isothiocyanate, 7.68 g of sarcosine ethyl ester hydrochloride, 12.5 g of triethyl amine, and 250 mL of chloroform. Crystallization from diethyl ether afforded the title compound (7.45 g) as a peach solid, m.p. 106°-108° C. Anal. Calcd. for C13H16N2OS: C, 62.87; H, 6.49; N, 11.28. Found: C, 62.52; H, 6.61; N, 11.29. Mass spectrum (+ESI, [M+H]+) m/z 269/271.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05861517 |
| 出典データセット | uspto-grants-1999_01 |
| ORD ID | ord-f1c6b312859a4c78bcd0f1c13f259615 |
| 出典メモ | uspto-grants-1999_01 |