化工社化工社 化学情報印刷レポート · 研究参考用
Triethylamine → 1-Ethyl-2-thioxo-3-(2,4,5-trimethylphenyl)-imidazolidin-4-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | 2,4,5-Trimethylphenyl isothiocyanate | HCID 140501 | — |
| 反応物 | N-Ethylglycine | HCID 316542 | — |
| 溶媒 | Chloroform | HCID 6212 | — |
| 生成物 | 1-Ethyl-2-thioxo-3-(2,4,5-trimethylphenyl)-imidazolidin-4-one | HCID 11357492 | 58.4% |
反応手順
The title compound was prepared by the procedure described in Example 9 using 17.7 g of 2,4,5-trimethylphenyl-isothiocyanate, 18.4 g of N-ethyl glycine, 20.2 g of triethyl amine, and 250 mL of chloroform. Crystallization from ethanol afforded the title compound (15.3 g) as an off-white solid, m.p. 162°-164° C. Anal. Calcd. for. C14H18N2OS: C, 64.09; H, 6.92; N, 10.68. Found: C, 64.21; H, 6.93; N, 10.80. Mass spectrum (EI, M.+) m/z 262.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05861517 |
| 出典データセット | uspto-grants-1999_01 |
| ORD ID | ord-4dae909f195046f28e8127ed3038fe23 |
| 出典メモ | uspto-grants-1999_01 |