化工社化工社 化学情報印刷レポート · 研究参考用
Acetone → 4-(6-Methoxy-2-naphthalenyl)-3-buten-2-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetone | HCID 180 | — |
| 反応物 | Water | HCID 962 | — |
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | 6-Methoxy-2-naphthaldehyde | HCID 76991 | — |
| 生成物 | 4-(6-Methoxy-2-naphthalenyl)-3-buten-2-one | HCID 53409926 | 98.2% |
反応手順
6-Methoxy-2-naphthaldehyde (1 g, 5.4 mmol) in acetone (5.0 g), with aqueous NaOH (0.25 g of 2.8% NaOH; 3.3 mol %) was stirred for 1 hour at 20° C. followed by 1 hour at reflux. Water (10 g) was added to precipitate the product which was filtered and dried to give 1.2 g (98% of theory) of 4-(6-methoxy-2-naphthyl)-3-buten-2-one. GC showed 99% conversion and 4% of a heavy co-product (95% of butenone).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05861538 |
| 出典データセット | uspto-grants-1999_01 |
| ORD ID | ord-01e1ab70bf85431185c7dbd1d6e5123e |
| 出典メモ | uspto-grants-1999_01 |