5-(4-Cyano-2-vinylphenyl)hydantoin → 5-(4-Cyano-2-ethylphenyl)hydantoin

HRID 343946ノート

反応式

HRID 343946 の反応式
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([CH:9]2[NH:13][C:12](=[O:14])[NH:11][C:10]2=[O:15])=[C:5]([CH:16]=[CH2:17])[CH:4]=1)#[N:2]>CO.[C].[Pd]>[C:1]([C:3]1[CH:8]=[CH:7][C:6]([CH:9]2[NH:13][C:12](=[O:14])[NH:11][C:10]2=[O:15])=[C:5]([CH2:16][CH3:17])[CH:4]=1)#[N:2]

参加物

4

反応物 1

HCID 700787825-(4-Cyano-2-vinylphenyl)hydantoin

生成物 1

HCID 700749315-(4-Cyano-2-ethylphenyl)hydantoin

試薬・触媒・溶媒 2

HCID 178418390HCID 178418390、化合物触媒HCID 887Methanol溶媒

実験手順

A solution of 5-(4-cyano-2-vinylphenyl)hydantoin (75 mg, 0.35 mmol) in methanol (20 ml) was shaken with 10% palladium-carbon (10 mg) under an atmosphere of hydrogen for 0.5 hours at 25 p.s.i. The catalyst was removed by filtration to give 5-(4-cyano-2-ethylphenyl)hydantoin in a quantitative yield as a colourless oil.

後処理

  1. customThe catalyst was removed by filtration

出典と根拠

ORDレコード
ord-608ac58e1aee4ed39d354c323246d5bc
出典データセット
uspto-grants-1999_01
特許番号
US05863947

反応ノート

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