反応式
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([CH:9]2[NH:13][C:12](=[O:14])[NH:11][C:10]2=[O:15])=[C:5]([C:16]#[C:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH:4]=1)#[N:2]>CO.[C].[Pd]>[C:1]([C:3]1[CH:8]=[CH:7][C:6]([CH:9]2[NH:13][C:12](=[O:14])[NH:11][C:10]2=[O:15])=[C:5]([CH2:16][CH2:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH:4]=1)#[N:2]参加物
4
実験手順
A solution of 5-[4-cyano-2-(2-phenylethynyl)phenyl]hydantoin (100 mg, 0.33 mmol) in methanol (20 ml) was shaken with 10% palladium-carbon (10 mg) under an atmosphere of hydrogen for 24 hours at 60 p.s.i. The catalyst was removed by filtration to give 5-[4-cyano-2-(2-phenylethyl)phenyl]hydantoin as a colourless oil.
後処理
- customThe catalyst was removed by filtration
出典と根拠
- ORDレコード
- ord-0ebda7467daf448680d696c08ef0e4de
- 出典データセット
- uspto-grants-1999_01
- 特許番号
- US05863947
関連ノート
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