化工社化工社 化学情報印刷レポート · 研究参考用
Oxalic Acid → Oxalic Acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Oxalic Acid | HCID 971 | — |
| 反応物 | 3,4-dihydro-2H-pyran | HCID 8080 | — |
| 反応物 | Tyrosol | HCID 10393 | — |
| 反応物 | Sodium Sulfate | HCID 24436 | — |
| 溶媒 | Acetone | HCID 180 | — |
| 生成物 | Oxalic Acid | HCID 971 | — |
| 生成物 | 4-(2-Tetrahydropyran-2-yloxyethyl)phenol | HCID 14208783 | — |
反応手順
Alternatively, suitable 4-(hydroxyalkyl)phenols or 4-(hydroxyalkyl)thiophenols may be protected in one step by combining a solution of the selected 4-(hydroxyalkyl)phenol or 4-(hydroxyalkyl)thiophenol in acetone with Na2SO4, dihydropyran, and a catalytic amount of oxalic acid. For example, 4-(2-hydroxyethyl)phenol in acetone is reacted with Na2SO4, distilled dihydropyran, and a catalytic amount of oxalic acid for three hours to yield 4-(2-tetrahydropyran-2-yloxyethyl)phenol (9).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04761420 |
| 出典データセット | uspto-grants-1988_08 |
| ORD ID | ord-5e7e6a073a6747c0a45822ef0a795ac2 |
| 出典メモ | uspto-grants-1988_08 |