化工社化工社 化学情報印刷レポート · 研究参考用
Hydrochloric Acid → Ammonia
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Phospho-L-tyrosine | HCID 30819 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | Ammonia | HCID 222 | — |
| 生成物 | Phospho-L-tyrosine | HCID 30819 | — |
反応手順
The tyrosine phosphate derivative VIII when treated with a mixture of 0.1M hydrochloric acid and tetrahydrofuran (1:1) at room temperature for 3 hours gave less than 5% loss of the phosphate group. Treatment of compound VIII with concentrated ammonia in a sealed tube for 5 hours at 60° C. gave rise to complete removal of both 2-cyanoethyl groups with only a trace of loss of phosphate.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05864032 |
| 出典データセット | uspto-grants-1999_01 |
| ORD ID | ord-debd17f443ba4611b13f3af1e8b81e49 |
| 出典メモ | uspto-grants-1999_01 |