化工社化工社 化学情報印刷レポート · 研究参考用
Benzyl Chloride → Methyl(4-benzylthiophenyl)acetate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzyl Chloride | HCID 7503 | — |
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | Methyl 2-(4-mercaptophenyl)acetate | HCID 14033178 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | Methyl(4-benzylthiophenyl)acetate | HCID 54174016 | — |
反応手順
Methyl(4-mercaptophenyl)acetate (0.2 mol) is heated at reflux with benzyl chloride (25 g, 0.2 mol) and K2CO3 (25 g, 0.2 mol) in 100 mL ethanol. The product is added to aqueous NaOH, extracted with ether, and purified by silica gel chromatography to yield methyl(4-benzylthiophenyl)acetate (3). (Scheme III, Step 1.)
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04761420 |
| 出典データセット | uspto-grants-1988_08 |
| ORD ID | ord-3bd374c3ce354367ba30e6cb8a4808a1 |
| 出典メモ | uspto-grants-1988_08 |