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Tetrahydrophthalic anhydride → N-(3-(allyloxy)-4-chlorophenyl)-3,4,5,6-tetrahydrophthalimide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Tetrahydrophthalic anhydride | HCID 6810 | — |
| 反応物 | 4-Chloro-3-[(prop-2-en-1-yl)oxy]aniline | HCID 54496113 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 生成物 | N-(3-(allyloxy)-4-chlorophenyl)-3,4,5,6-tetrahydrophthalimide | HCID 12881900 | — |
反応手順
A mixture of 4.4 g of THPA, 5.3 g of 3B and 60 mL of glacial acetic acid was refluxed for 1 hour, then poured into 300 mL of ice water. The resulting mixture was allowed to stand for 10 minutes, then filtered. The collected solid was washed with cold water, dried under reduced pressure and recrystallized from ethyl acetate/hexane, to give N-(3-(allyloxy)-4-chlorophenyl)-3,4,5,6-tetrahydrophthalimide (3C), as yellow crystals, m.p.: 118.5°-120° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05053071 |
| 出典データセット | uspto-grants-1991_10 |
| ORD ID | ord-93160ebf2a4a4814a78be9c823f58fad |
| 出典メモ | uspto-grants-1991_10 |