化工社化工社 化学情報印刷レポート · 研究参考用
1,2-Dibromoethane → 4-Hydroxypyrimidine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1,2-Dibromoethane | HCID 7839 | — |
| 反応物 | 1-Bromo-2-Chloroethane | HCID 7849 | — |
| 反応物 | 4-Hydroxypyrimidine | HCID 20695 | — |
| 生成物 | 4-Hydroxypyrimidine | HCID 20695 | — |
| 生成物 | 2-(1,6-Dihydro-6-oxopyrimidin-1-yl)ethyl chloride | HCID 19772555 | — |
反応手順
When an equivalent amount of 4-pyrimidone is substituted for 1-ethoxycarbonyl-2H-indazolin-3-one and 2-bromochloroethane is substituted for 1,2-dibromoethane in the procedure of Example 19, 2-(1,6-dihydro-6-oxopyrimidin-1-yl)ethyl chloride is isolated after column chromatography (4-pyrimidone, Aldrich, 34%, B).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05053411 |
| 出典データセット | uspto-grants-1991_10 |
| ORD ID | ord-51b4306f523143c698d0cc229d69e0d4 |
| 出典メモ | uspto-grants-1991_10 |