Butoxy(oxo)acetate → Butyl 2-oxo-2-((3-(2H-tetrazol-5-yl)phenyl)amino)acetate
反応式
[NH2:1][C:2]1[CH:3]=[C:4]([C:8]2[NH:12][N:11]=[N:10][N:9]=2)[CH:5]=[CH:6][CH:7]=1.[CH2:13]([O:17][C:18](=[O:22])[C:19]([O-])=[O:20])[CH2:14][CH2:15][CH3:16]>>[CH3:16][CH2:15][CH2:14][CH2:13][O:17][C:18]([C:19]([NH:1][C:2]1[CH:3]=[C:4]([C:8]2[N:12]=[N:11][NH:10][N:9]=2)[CH:5]=[CH:6][CH:7]=1)=[O:20])=[O:22]参加物
3
実験手順
5-(3-Aminophenyl)tetrazole (1.7 g) was added to 12 ml of n-butyloxalate and reacted at a bath temperature of 165° to 175° C. for 1.5 hr while stirring. After cooling, the precipitated crystals were filtered off and recrystallized from acetone-n-hexane, to give 2.3 g (yield: 75%) of 5-(3-n-butyloxalylaminophenyl)tetrazole.
後処理
- customreacted at a bath temperature of 165° to 175° C. for 1.5 hr
- temperatureAfter cooling
- filtrationthe precipitated crystals were filtered off
- customrecrystallized from acetone-n-hexane
出典と根拠
- ORDレコード
- ord-7783e3201b35458f99cdad4e8b609dc6
- 出典データセット
- uspto-grants-1991_10
- 特許番号
- US05055481
反応ノート
読み込み中…