4-Carbethoxycinnamic acid → 4-Ethoxycarbonylbenzenepropanoic acid
反応式
[C:1]([C:6]1[CH:16]=[CH:15][C:9]([CH:10]=[CH:11][C:12]([OH:14])=[O:13])=[CH:8][CH:7]=1)([O:3][CH2:4][CH3:5])=[O:2]>CCO.[Rh]>[CH2:4]([O:3][C:1]([C:6]1[CH:16]=[CH:15][C:9]([CH2:10][CH2:11][C:12]([OH:14])=[O:13])=[CH:8][CH:7]=1)=[O:2])[CH3:5]参加物
4
実験手順
A solution of 4-carbethoxycinnamic acid (4.9 g) in EtOH (120 ml) was hydrogenated over 5% Rh/C (485 mg) at atmospheric pressure for 21 hr. The solution was filtered and stripped. The residue was crystallized from cyclohexane to afford 2.23 g (46%) of the title compound as white crystals; mp 108.5°-110.5°.
後処理
- filtrationThe solution was filtered
- customThe residue was crystallized from cyclohexane
出典と根拠
- ORDレコード
- ord-ece937894f644ec9864f6d6f677afbf5
- 出典データセット
- uspto-grants-1991_10
- 特許番号
- US05055450
反応ノート
読み込み中…