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Toluene → 2-[4-(4,6-Bis-trichloromethyl-s-triazin-2-yl)benzoylmethylene]-1,3,3-trimethyl-indoline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Toluene | HCID 1140 | — |
| 反応物 | 1,3,3-Trimethyl-2-methyleneindoline | HCID 8351 | — |
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | HCID 14473251 | HCID 14473251 | — |
| 溶媒 | Water | HCID 962 | — |
| 溶媒 | Diethyl Ether | HCID 3283 | — |
| 生成物 | 2-[4-(4,6-Bis-trichloromethyl-s-triazin-2-yl)benzoylmethylene]-1,3,3-trimethyl-indoline | HCID 86745139 | — |
反応手順
4-(4,6-Bis-trichloromethyl-s-triazin-2-yl)benzoylchloride (15.4 pbw) are added dropwise with stirring at 10° C. to 5.2 pbw of 1,3,3-trimethyl-2-methylene-indoline and 10.6 pbw of triethylamine in 140 pbw of anhydrous toluene. The mixture is stirred for 3 hours at room temperature. It is then admixed with 100 pbw of water and 200 pbw of ether and extracted by shaking. The dried organic phase is concentrated. The residue is recrystallized from 2-methoxy-ethanol, giving red-orange crystals.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05055579 |
| 出典データセット | uspto-grants-1991_10 |
| ORD ID | ord-0e364f3de92147eebb472fe12c1927e9 |
| 出典メモ | uspto-grants-1991_10 |