化工社化工社 化学情報印刷レポート · 研究参考用
Water → 2-Benzylcyclohexan-1-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | Benzyl Chloride | HCID 7503 | — |
| 反応物 | 1-Cyclohexylpyrrolidine | HCID 139064 | — |
| 溶媒 | 1,4-Dioxane | HCID 31275 | — |
| 生成物 | 2-Benzylcyclohexan-1-one | HCID 98945 | — |
反応手順
A mixture of 1-(1-pyrrolidinyl)cyclohexane (85.4 g) and benzyl chloride (100 ml) in dioxane (400 ml) was heated under reflux for 23 hours under nitrogen. Water (100 ml) was then added and the brown oil was distilled to give (2RS)-2-phenylmethylcyclohexanone (47.1 g).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05057513 |
| 出典データセット | uspto-grants-1991_10 |
| ORD ID | ord-21da1710588a4bcabd47799acedec4b2 |
| 出典メモ | uspto-grants-1991_10 |