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Hydrochloric Acid → Methyl 4-benzyloxybenzimidate hydrochloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Tetrahydrofuran | HCID 8028 | — |
| 反応物 | 4-Benzyloxybenzonitrile | HCID 561371 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | Methyl 4-benzyloxybenzimidate hydrochloride | HCID 12222189 | — |
反応手順
A solution of 560 mg of 4-benzyloxybenzonitrile in 16 ml of THF and 0.2 ml of methanol, cooled to 0° C., was saturated with hydrogen chloride and kept at 4° C. for 16 hours. The precipitate was filtered off, washed with diethyl ether and dried to give 357 mg of methyl 4-benzyloxybenzimidate hydrochloride, m.p. 179°-180° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05057614 |
| 出典データセット | uspto-grants-1991_10 |
| ORD ID | ord-7456a4145aae444eb85ca8084af499b7 |
| 出典メモ | uspto-grants-1991_10 |