化工社化工社 化学情報印刷レポート · 研究参考用
Water → HCID 178471933、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | 2,4-Difluoroaniline | HCID 9709 | — |
| 反応物 | Ethyl 3-ethoxy-2-(2,3,4,5,6-pentafluorobenzoyl)-acrylate | HCID 53952225 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | HCID 178471933 | HCID 178471933 | 94.5% |
反応手順
44.3 g of 2,4-difluoroaniline are added dropwise to a solution of 115 g of ethyl 3-ethoxy-2-(2,3,4,5,6-pentafluorobenzoyl)-acrylate in 380 ml of ethanol, while cooling with ice and stirring. The mixture is stirred at room temperature for 1 hour, 380 ml of water are added, while cooling with ice, and the precipitate is filtered off with suction, washed with ethanol/H2O (1:1) and dried. 135.4 g of the title compound of melting point 97°-99° C. are obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05059597 |
| 出典データセット | uspto-grants-1991_10 |
| ORD ID | ord-778ffdc1a0364023b5c95adefd9bafaf |
| 出典メモ | uspto-grants-1991_10 |