化工社化工社 化学情報印刷レポート · 研究参考用
Oxygen → 4-(3-Dodecanoyloxypropyl)-5-hydroxy-2(5H)-furanone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Oxygen | HCID 977 | — |
| 反応物 | Rose Bengal Lactone | HCID 69439 | — |
| 反応物 | 3-(2-Trimethylsilyl-4-furyl)propyl dodecanoate | HCID 15037127 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | 4-(3-Dodecanoyloxypropyl)-5-hydroxy-2(5H)-furanone | HCID 15037128 | — |
反応手順
A mixture of 3-(5-trimethylsilyl-3-furyl)propyl dodecanoate (105 mg, 0.27 mmol) and Rose Bengal (5 mg) in tetrahydrofuran (6 ml) was exposed to singlet oxygen for 2.5 hours at -78°. The residue, after solvent removal, was purified by preparative thin layer chromatography (TLC) (20×20 cm, 500μ silica plate; developed with 60% ethyl ether/petroleum ether). The title ester was obtained as an off-white solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05059611 |
| 出典データセット | uspto-grants-1991_10 |
| ORD ID | ord-2ac8e85efa0a4a908b626a580ff5f49d |
| 出典メモ | uspto-grants-1991_10 |