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Acetic Acid → 2-Furyltrimethylsilane
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetic Acid | HCID 176 | — |
| 反応物 | Piperidine | HCID 8082 | — |
| 反応物 | 3-(2-Trimethylsilyl-4-furyl)propan-1-al | HCID 15037092 | — |
| 反応物 | 2,2-Dioctylpropanedioate | HCID 22059025 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | 2-Furyltrimethylsilane | HCID 137092 | — |
反応手順
3-(2-Trimethylsilyl-4-furyl)propan-1-al is reacted with dioctylmalonate in tetrahydrofuran in the presence of acetic acid and piperidine to give 3-[4,4-di (carbooctanoxy)-3-butenyl]- 5-trimethylsilylfuran which is treated with cold aqueous potassium hydroxide to give 3-(4-carboxy-4-carbooctanoxy-3-butenyl)-5-trimethylsilylfuran.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05059611 |
| 出典データセット | uspto-grants-1991_10 |
| ORD ID | ord-f22021f889e543469ccef2e7d86fe91e |
| 出典メモ | uspto-grants-1991_10 |