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Bromine → 2-Bromo-3,4-dihydro-7-methoxy-1(2H)-naphthalenone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Bromine | HCID 24408 | — |
| 反応物 | 7-Methoxy-1,2,3,4-tetrahydronaphthalen-1-one | HCID 81276 | — |
| 溶媒 | Diethyl Ether | HCID 3283 | — |
| 生成物 | 2-Bromo-3,4-dihydro-7-methoxy-1(2H)-naphthalenone | HCID 311906 | 87.2% |
反応手順
To a 10° C. solution of 25 g (0.142 mol) of 7-methoxy-3,4-dihydro-1(2H)-naphthalenone in 1 liter ether was added dropwise (maintaining reaction temperature at about 10° C.) 37.9 g (0.237 mol) of bromine. The reaction solution was concentrated on a rotating evaporator and the residue crystallized from ether to give 31.6 g (87%) of present title compound, m.p. 79°-80° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05059609 |
| 出典データセット | uspto-grants-1991_10 |
| ORD ID | ord-407b83681b2f42e0a0bdbfab46312e39 |
| 出典メモ | uspto-grants-1991_10 |