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Cyclohexanone → 1,1-Dimethoxycyclohexane
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Cyclohexanone | HCID 7967 | — |
| 反応物 | Trimethyl orthoformate | HCID 9005 | — |
| 反応物 | Sodium Methoxide | HCID 10942334 | — |
| 触媒 | Sulfuric Acid | HCID 1118 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | 1,1-Dimethoxycyclohexane | HCID 13616 | — |
反応手順
A mixture of cyclohexanone (52 ml, 0.5 mol), trimethylorthoformate (66 ml, 0.6 mol), methanol (51 ml, 1.26 mol) and concentrated H2SO4 (1 drop) was refluxed for 18 hours. A solution sodium methoxide in methanol was added until the mi was neutral, and the mixture was fractionally distilled. 1,1-Dimethoxycyclohexane was obtained from the fraction b.p. 162°-164° C. (50.6 g, 70%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05061626 |
| 出典データセット | uspto-grants-1991_10 |
| ORD ID | ord-8d809266f66b474db9ff18eb07c694bf |
| 出典メモ | uspto-grants-1991_10 |