関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Isoflurane | HCID 3763 | — |
| 反応物 | Potassium Fluoride | HCID 522689 | — |
| 生成物 | Desflurane | HCID 42113 | 29% |
反応手順
12.9 g of isoflurane (FORANE® isoflurane commercially available from Anaquest Division of BOC, Inc. in Madison, Wis.) were combined with 5.5 g of potassium fluoride and 20 ml of diethylglycol and the mixture was heated with stirring for 10 hours in a glass pressure vessel at 195° C. The heated mixture was washed with ice water and the organic layer was subjected to gas chromatography, which showed the presence of the compound CHF2OCHFCF3 (29% yield).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04762856 |
|---|
| 出典データセット | uspto-grants-1988_08 |
|---|
| ORD ID | ord-18aec9d14c6b448389c5aa7c859e12fe |
|---|
| 出典メモ | uspto-grants-1988_08 |
|---|
