反応式
[CH3:1][C:2]1([CH3:25])[CH2:11][CH2:10][C:9]([CH3:13])([CH3:12])[C:8]2[CH:7]=[C:6]([CH2:14][C:15]3[CH:16]=[C:17]([CH:20]4OCC[O:21]4)[O:18][CH:19]=3)[CH:5]=[CH:4][C:3]1=2.Cl>C1COCC1>[CH3:1][C:2]1([CH3:25])[CH2:11][CH2:10][C:9]([CH3:12])([CH3:13])[C:8]2[CH:7]=[C:6]([CH2:14][C:15]3[CH:16]=[C:17]([CH:20]=[O:21])[O:18][CH:19]=3)[CH:5]=[CH:4][C:3]1=2参加物
4
実験手順
A round bottom flask was mixed with 2-{4-[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro- 2-naphthalenyl)methyl]-2-furyl}-1,3-dioxolane (246 mg, 0.72 mmol), 3.0 N HCl (10 mL) and THF (20 mL). The reaction mixture stirred for 16 hours at room temperature and was concentrated to one half volume. The resulting mixture was partitioned between saturated NaCl and ether. The ether layer was dried over MgSO4 and concentrated to dryness. The resulting oil showed an inseparable impurity by TLC and the product was used without further purification.
後処理
- concentrationwas concentrated to one half volume
- customThe resulting mixture was partitioned between saturated NaCl and ether
- dry with materialThe ether layer was dried over MgSO4
- concentrationconcentrated to dryness
- customthe product was used without further purification
出典と根拠
- ORDレコード
- ord-bce71868654642e69db07a6b4dc933fd
- 出典データセット
- uspto-grants-2007_02
- 特許番号
- US07173134B2
関連ノート
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