Acetic Anhydride → 1,5-Diacetyl-3-(ethoxy-phenyl-methylidene)-2-indolinone

HRID 347952

反応式

HRID 347952 の反応式
[C:1]([N:4]1[C:12]2[C:7](=[CH:8][C:9]([C:13](=[O:15])[CH3:14])=[CH:10][CH:11]=2)[CH2:6][C:5]1=[O:16])(=[O:3])[CH3:2].[C:17]([O:20][C:21](=O)[CH3:22])(=O)[CH3:18]>CCOC(OCC)(OCC)C1C=CC=CC=1>[C:1]([N:4]1[C:12]2[C:7](=[CH:8][C:9]([C:13](=[O:15])[CH3:14])=[CH:10][CH:11]=2)[C:6](=[C:17]([O:20][CH2:21][CH3:22])[C:18]2[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=2)[C:5]1=[O:16])(=[O:3])[CH3:2]

参加物

4

反応物 2

HCID 7918Acetic AnhydrideHCID 210845601,5-Diacetyl-2-indolinone

生成物 1

HCID 689919611,5-Diacetyl-3-(ethoxy-phenyl-methylidene)-2-indolinone

試薬・触媒・溶媒 1

HCID 74268Benzene, (triethoxymethyl)-溶媒2 回

実験手順

32.6 g (150 mmol) 1,5-diacetyl-2-indolinone are suspended in 100 ml triethyl orthobenzoate and stirred overnight with 150 ml acetic anhydride at 110° C. Then a further 50 ml triethyl orthobenzoate are added and the mixture is stirred for a further 24 h. Then it is evaporated down and the resulting precipitate is suction filtered, washed and dried.

後処理

  1. customThen it is evaporated down
  2. filtrationfiltered
  3. washwashed
  4. customdried

出典と根拠

ORDレコード
ord-05c85fbcbf0d48e6b86502da5c42840b
出典データセット
uspto-grants-2007_02
特許番号
US07176231B2

関連ノート

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