Acetic Anhydride → 1-Acetyl-5-butyryl-3-(ethoxy-phenyl-methylidene)-2-indolinone

HRID 347960

反応式

HRID 347960 の反応式
[C:1]([C:6]1[CH:7]=[C:8]2[C:12](=[CH:13][CH:14]=1)[NH:11][C:10](=[O:15])[CH2:9]2)(=[O:5])[CH2:2][CH2:3][CH3:4].[CH3:16][CH2:17][O:18][C:19](OCC)(OCC)[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1.[C:32](OC(=O)C)(=[O:34])[CH3:33]>>[C:32]([N:11]1[C:12]2[C:8](=[CH:7][C:6]([C:1](=[O:5])[CH2:2][CH2:3][CH3:4])=[CH:14][CH:13]=2)[C:9](=[C:19]([O:18][CH2:17][CH3:16])[C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[C:10]1=[O:15])(=[O:34])[CH3:33]

参加物

4

反応物 3

HCID 7918Acetic AnhydrideHCID 74268Benzene, (triethoxymethyl)-HCID 235593785-Butyryl-2-indolinone

生成物 1

HCID 689930531-Acetyl-5-butyryl-3-(ethoxy-phenyl-methylidene)-2-indolinone

反応条件

温度
100 °C

実験手順

10 g (49 mmol) 5-butyryl-2-indolinone (Ex. I.2) in 200 ml acetic anhydride are stirred for 5 h at 130° C. Then 35 ml triethyl orthobenzoate are added and the mixture is stirred for a further 4 h at 100° C. It is then evaporated down and the resulting precipitate is suction filtered, washed and dried.

後処理

  1. customIt is then evaporated down
  2. filtrationfiltered
  3. washwashed
  4. customdried

出典と根拠

ORDレコード
ord-8abcb86c2e68461dac488cb4954908da
出典データセット
uspto-grants-2007_02
特許番号
US07176231B2

関連ノート

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