HCID 68839044、化合物 → 4,6-Dihydrothieno(3,4-c)furan-1,3-dione
反応式
CO[C:3]([CH:5]1[CH2:9][S:8][CH2:7][C:6]1(O)[C:10]([OH:12])=[O:11])=[O:4]>C(OC(=O)C)(=O)C>[S:8]1[CH2:7][C:6]2[C:10]([O:12][C:3](=[O:4])[C:5]=2[CH2:9]1)=[O:11]参加物
3
実験手順
A solution of 3-hydroxy tetrahydro thiophene-3,4-dicarboxylicacid-4-methylester (2.87 g, 14.9 mmol) in acetic anhydride (20 ml) was refluxed for 4 h. The reaction mixture was filtered and concentrated under reduce pressure. The solid residue was triturated with acetone, dried with Na2SO4 and concentrated in vacuo. The solid product was recrystallized from benzene to give 2,5-dihydrothiophene-3,4-dicarboxylic anhydride in 26% yield.
後処理
- filtrationThe reaction mixture was filtered
- concentrationconcentrated
- customThe solid residue was triturated with acetone
- dry with materialdried with Na2SO4
- concentrationconcentrated in vacuo
- customThe solid product was recrystallized from benzene
出典と根拠
- ORDレコード
- ord-e59402433d0546e589a217e6b856568b
- 出典データセット
- uspto-grants-2007_02
- 特許番号
- US07176241B2
反応ノート
読み込み中…