Phosphorus oxychloride → HCID 14256186、化合物

HRID 34830ノート

反応式

HRID 34830 の反応式
[P:1]([Cl:5])(Cl)([Cl:3])=[O:2].[Br:6][CH2:7][CH:8]([OH:10])[CH3:9]>C(Cl)(Cl)(Cl)Cl>[Br:6][CH2:7][CH:8]([O:10][P:1]([Cl:5])([Cl:3])=[O:2])[CH3:9]

参加物

4

反応物 2

HCID 24813Phosphorus oxychlorideHCID 297401-Bromo-2-propanol

生成物 1

HCID 14256186HCID 14256186、化合物収率 42.2%

試薬・触媒・溶媒 1

HCID 5943Carbon Tetrachloride溶媒

実験手順

To a solution of 46 g of phosphorus oxychloride in 110 ml of carbon tetrachloride was added with stirring 21 g of 1-bromo-2-propanol. The mixture was stirred overnight, the solvent removed and the residue evaporated twice from toluene at 35° C., then evaporated to dryness giving a dark oil. This oil was distilled on a Kugelrohr at 75° C., 0.3 mm giving 16.3 g of the desired compound as a white oil.

後処理

  1. customthe solvent removed
  2. customthe residue evaporated twice from toluene at 35° C.
  3. customevaporated to dryness
  4. customgiving a dark oil
  5. distillationThis oil was distilled on a Kugelrohr at 75° C.

出典と根拠

ORDレコード
ord-e3ab952f95f3447d8425a816cc6768d0
出典データセット
uspto-grants-1988_08
特許番号
US04762942

反応ノート

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