化工社化工社 化学情報印刷レポート · 研究参考用
Ethyl Acetate → HCID 86760394、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethyl Acetate | HCID 8857 | — |
| 反応物 | 3-Amino-N-butylbenzenesulfonamide | HCID 5137973 | — |
| 反応物 | [5-(4-Fluorophenylcarbamoyl)pyrimidin-2-yloxy]acetic acid | HCID 21087356 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | HCID 86760394 | HCID 86760394 | 27% |
反応手順
The titled compound was prepared from [5-(4-fluorophenylcarbamoyl)pyrimidin-2-yloxy]acetic acid using 3-amino-N-butyl-benzenesulfonamide (53 mg, 0.21 mmol) as the coupling partner. Chromatography (1:1 ethyl acetate:dichloromethane) through SiO2 yielded 23 mg (27%) of the titled compound. ESI-MS m/z 502 (MH+), 500 (M−H−).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07176310B1 |
| 出典データセット | uspto-grants-2007_02 |
| ORD ID | ord-c61610a7835242e8bdb1272920cfc583 |
| 出典メモ | uspto-grants-2007_02 |