化工社化工社 化学情報印刷レポート · 研究参考用
Trimethyl orthoformate → Methyl 1-methyl-1H-benzo[d]imidazole-5-carboxylate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Trimethyl orthoformate | HCID 9005 | — |
| 反応物 | Methyl 3-amino-4-(methylamino)benzoate | HCID 15586064 | — |
| 生成物 | Methyl 1-methyl-1H-benzo[d]imidazole-5-carboxylate | HCID 965319 | — |
反応手順
A solution of methyl 3-amino-4-methylaminobenzoate (prepared as in DE 1990390463 A1) (2.57 g, 14 mmol) in trimethyl orthoformate (50 mL) was refluxed for 16 hours. The solvent was then removed under reduced pressure to afford 2.31 g of product.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07176322B2 |
| 出典データセット | uspto-grants-2007_02 |
| ORD ID | ord-32dc8e7f00a3425182a33ced2a8f8734 |
| 出典メモ | uspto-grants-2007_02 |