Triphenylphosphine → (3-Cyanopropyl)triphenylphosphonium bromide

HRID 348746

反応式

HRID 348746 の反応式
[C:1]1([P:7]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Br:20][CH2:21][CH2:22][CH2:23][C:24]#[N:25]>C1(C)C=CC=CC=1>[Br-:20].[C:24]([CH2:23][CH2:22][CH2:21][P+:7]([C:1]1[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1)([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1)#[N:25]

参加物

4

反応物 2

HCID 11776TriphenylphosphineHCID 214124-Bromobutyronitrile

生成物 1

HCID 3036619(3-Cyanopropyl)triphenylphosphonium bromide収率 50.6%

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

実験手順

Triphenylphosphine (1.4789 g) was dissolved in anhydrous toluene (44.4 ml) and then added with 4-bromo-butyronitrile (manufactured by Tokyo Kasei Kogyo Co., Ltd.) (834.7 mg), followed by thermal reflux for 22 hours. After the reaction, a precipitated product was filtrated. The precipitate obtained through filtration was washed with toluene and thermally dried under reduced pressure, thereby obtaining the subject compound (1.1697 g) as a white solid.

後処理

  1. temperatureby thermal reflux for 22 hours
  2. customAfter the reaction
  3. filtrationa precipitated product was filtrated
  4. customThe precipitate obtained through filtration
  5. washwas washed with toluene
  6. customthermally dried under reduced pressure

出典と根拠

ORDレコード
ord-d7a84e5bd46549759e2c17077a7be90a
出典データセット
uspto-grants-2007_02
特許番号
US07176227B2

関連ノート

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