関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | Iodine chloride | HCID 24640 | — |
| 反応物 | Benzoic acid, 4-hydroxy-3-nitro-, methyl ester | HCID 66835 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 生成物 | Methyl 4-hydroxy-3-iodo-5-nitrobenzoate | HCID 21086206 | 91,075.398% |
反応手順
To a solution of methyl 4-hydroxy-3-nitrobenzoate (2.0 g) in acetic acid (15 mL) was added iodine monochloride (1.65 mg) in acetic acid, and the mixture was stirred at 100° C. for 1.5 h. After cooling to room temperature, the mixture was poured into water (200 mL), and stirred for 30 min. The mixture was filtered and washed with water and hexanes. The yellow powder was collected by filtration and dried in vacuum oven overnight to give 2.99 g of the title compound: 1H NMR (300 MHz, CDCl3) δ 11.68, 8.81, 8.72, 3.96.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07176242B2 |
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| 出典データセット | uspto-grants-2007_02 |
|---|
| ORD ID | ord-ce3a917d547b4565ad207f5df577f15f |
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| 出典メモ | uspto-grants-2007_02 |
|---|
