化工社化工社 化学情報印刷レポート · 研究参考用
Methyl quinoline-7-carboxylate → Methyl 1,2,3,4-tetrahydroquinoline-7-carboxylate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methyl quinoline-7-carboxylate | HCID 12554532 | — |
| 触媒 | Adams' catalyst | HCID 345198 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | Methyl 1,2,3,4-tetrahydroquinoline-7-carboxylate | HCID 16244389 | 98.8% |
反応手順
A solution of methyl quinoline-7-carboxylate (185 mg, 1.0 mmol) and PtO2 (20 mg) in methanol (10 mL) was shaken under an atmosphere of hydrogen for 2 h. The reaction mixture was filtered through diatomaceous earth, and concentrated under reduced pressure to provide methyl 1,2,3,4-tetrahydroquinoline-7-carboxylate (189 mg): ESI MS m/z 192 [M+H]+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07176242B2 |
| 出典データセット | uspto-grants-2007_02 |
| ORD ID | ord-02acc3f835484419afed0281129fcee5 |
| 出典メモ | uspto-grants-2007_02 |