Hydrochloric Acid → 4-Aminomethyl-1-propyl-5-aminopyrazole dihydrochloride
反応式
[NH2:1][CH2:2][C:3]1[CH:4]=[N:5][N:6]([CH2:28][CH2:29][CH3:30])[C:7]=1[NH:8]C(C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1.[ClH:31]>C(OCC)(=O)C.CO>[ClH:31].[ClH:31].[NH2:1][CH2:2][C:3]1[CH:4]=[N:5][N:6]([CH2:28][CH2:29][CH3:30])[C:7]=1[NH2:8]参加物
5
実験手順
To a solution of 4-aminomethyl-1-propyl-5-tritylaminopyrazole (9.6 g) in a mixture of ethyl acetate (150 ml) and methanol (30 ml) was added 4N hydrochloric acid in ethyl acetate (24.2 ml), and the mixture was stirred at room temperature for 2 hours. The resulting precipitate was collected by filtration and dried in vacuo to give 4-aminomethyl-1-propyl-5-aminopyrazole dihydrochloride (3.3 g).
後処理
- filtrationThe resulting precipitate was collected by filtration
- customdried in vacuo
出典と根拠
- ORDレコード
- ord-48cce846ece7415caa44208aa6bb34a2
- 出典データセット
- uspto-grants-2007_02
- 特許番号
- US07179801B2
反応ノート
読み込み中…